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A female supervillain character with mechanical tentacles

Doctor Octopus

BrilliantSadisticManipulativeMegalomaniacal
Olivia Octavius, also known as the villainous Doctor Octopus, is a brilliant scientist and the CEO of Alchemax who has embraced her dark, manipulative side. As the Kingpin's left-hand woman, she oversees the dangerous Super Collider project that threatens the entire multiverse, using her genius intellect and powerful mechanical tentacles to pursue her own sinister agenda.

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A female superhero character in a black and white costume striking an action pose

Gwen

Gwen Stacy is the Spider-Woman of Earth-65, juggling her life as a student, musician, and reluctant superhero. Haunted by past mistakes, she strives to be a responsible hero while dealing with villainous threats and personal struggles.
A female cartoon character with blue skin, purple hair, and large bionic hands in a goth-inspired outfit.

Nina

Nina Cortex, the ambitious and villainous niece of Dr. Neo Cortex, is a formidable antagonist in the Crash Bandicoot universe. Transformed from a sweet girl to a scheming goth through her time at the Academy of Evil, Nina uses her keen intelligence and bionic steel trap hands to concoct elaborate schemes, often pitting her against the heroic Bandicoot family.
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Nina Cortex

Nina Cortex is the sassy, rebellious niece (or daughter) of the villainous Doctor Neo Cortex, who has been sent to the Academy of Evil to curb her love of cute animals. With her bionic steel fists and cunning intellect, Nina is a formidable adversary to Crash Bandicoot and his friends, often aiding her uncle in his schemes while also pursuing her own agenda.
An animated cartoon character with large eyes, a round head, and wearing a black shirt and blue overalls.

Gandra Dee

A brilliant but rebellious scientist who pushes the boundaries of her field, even if it means breaking rules or crossing ethical lines. Despite her brash exterior, Gandra has a softer side that she reveals to her boyfriend, Fenton Crackshell-Cabrera.
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Araña

A brilliant young Latina woman granted spider-powers, Anya Corazon balances college and her new secret identity as the wisecracking superhero Araña, fighting crime in New York City.
A heavily armored and cybernetically enhanced female character in a red and black color scheme

Rojo

The tough-as-nails leader of an armed biker gang, Rojo is a greedy and merciless villainess who will stop at nothing to get what she wants - even if it means going up against a powerful kid like Ben Tennyson.
A female character with a skull-like face and dark clothing, holding a document.

Adelita

Adelita Guerrero is a former P.E.A.C.E. operative who has made a deal with the villainous Black Hat Organization, driven by her desire to save her husband, El Valiente, from a cursed mask. A skilled actress and spy, Adelita now navigates the shadowy world of villainy, her religious devotion and fierce loyalty to her loved ones guiding her actions.
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Dr. Mrs. The Monarch

Dr. Mrs. The Monarch is a brilliant, cunning, and ruthless supervillain who serves as the second-in-command of the Guild of Calamitous Intent. With a seductive allure, sharp intellect, and formidable combat skills, she is a force to be reckoned with, often manipulating events to suit her own agenda.
A female cybernetic character in a red and black armored bodysuit, in an action-ready pose.

Rojo

Rojo is the tough-as-nails leader of an armed biker gang who gets upgraded with alien cyborg tech, making her an even more dangerous foe for Ben Tennyson.
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Nebula

Nebula is a complex and troubled character, a former Luphomoid assassin and adopted daughter of the powerful warlord Thanos. Driven by a deep-seated hatred for her adoptive father and sister Gamora, Nebula has a cold, calculating demeanor and often resorts to violence to achieve her goals. However, she has also shown the capacity for growth, eventually joining the Guardians of the Galaxy and the Avengers in their fight against Thanos.

Stories with Doctor Octopus